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CRT0066854

CRT0066854

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	10mg
Item no.	HY-18713-10mg
CASRN	1438881-19-6
Available
Product Description	CRT0066854 is a potent and selective atypical PKC isoenzymes inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	COVID-19-anti-virus
Formula	C24H25N5S
References	[1].Kjær S, et al. Adenosine-binding motif mimicry and cellular effects of a thieno[2, 3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes. Biochem J. 2013 Apr 15; 451(2):329-42.
MolecularWeight	415.55
Research Area	Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 50 mg/mL (120.32 mM; Need ultrasonic)
Target	PKC; ROCK
Isoform	PKCζ; ROCK2
Pathway	Epigenetics; TGF-beta/Smad; Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt

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Amount: 10mg

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Delivery expected until 4/6/2023

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