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CRT0066854 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 5mg
Item no. HY-18713-5mg
CASRN 1438881-19-6
Available
Product Description
CRT0066854 is a potent and selective atypical PKC isoenzymes inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.
StorageTemperature
Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications
COVID-19-anti-virus
Formula
C24H25N5S
References
[1].Kjær S, et al. Adenosine-binding motif mimicry and cellular effects of a thieno[2, 3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes. Biochem J. 2013 Apr 15; 451(2):329-42.
MolecularWeight
415.55
Research Area
Inflammation/Immunology; Neurological Disease
Solubility
DMSO : 50 mg/mL (120.32 mM; Need ultrasonic)
Target
PKC; ROCK
Isoform
PKCζ; ROCK2
Pathway
Epigenetics; TGF-beta/Smad; Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 5mg
Available: In stock
available

Delivery expected until 4/6/2023 

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