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Ranitidine (hydrochloride)

Ranitidine (hydrochloride)

Item no.	HY-B0281A-100mg
Manufacturer	MedChem Express
CASRN	66357-59-3
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 500 mg
Category	Food Safety Histamines Cell Biology Cytoskeleton Inhibitors & Compound Libraries Small Molecules small GTPases Ran Subfamily
Type	Inhibitors
Specific against	other
Purity	99.86
Citations	[1]Daly MJ, et al. Some in vitro and in vivo actions of the new histamine H2-receptor antagonist, ranitidine. Br J Pharmacol. 1981 Jan;72(1):49-54.\|[2]Vila-Leahey A, et al. Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice. Oncoimmunology. 2016 Mar 10;5(7):e1151591.
Smiles	CN/C(NCCSCC1=CC=C(CN(C)C)O1)=C\[N+]([O-])=O.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	66357-59-3
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Histamine Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	350.86
Product Description	Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine hydrochloride antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride inhibits breast tumor development and spread in mice[1][2].
Manufacturer - Research Area	Cancer; Metabolic Disease
Solubility	DMSO: 50 mg/mL (ultrasonic)\|H2O: ≥ 50 mg/mL
Manufacturer - Pathway	GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Isoform	H2 Receptor
Clinical information	Launched

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HY-B0281A-100mg-safety-datasheet.pdf