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DFP00173

DFP00173

Manufacturer	ChemScene
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Amount	50mg
Item no.	CS-0090372-50mg
eClass 6.1	32169090
eClass 9.0	32169090
Available
CAS	672286-03-2
Purity	>98%
MWt	332.16
Formula	C11H7Cl2N3O3S
Solubility	DMSO : 125 mg/mL (376.32 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC₅₀ of ?0.1-0.4 uM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9^[1]. In Vitro: DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC₅₀ of ca.0.2 uM^[1].
Research Area	Cancer; Inflammation/Immunology

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Amount: 50mg

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Delivery expected until 6/6/2024