Recombinant Human B- and T-lymphocyte attenuator (BTLA), partial (Active)

Proteins / Recombinant Protein

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Lyophilized from a 0.2 ?m filtered PBS, 6% Trehalose, pH 7.4

Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).

Partial

Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Homo sapiens (Human)

Less than 1.0 EU/ug as determined by LAL method.