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Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein (His Tag)

Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein (His Tag)

Item no.	10594-H08H1-1
Manufacturer	Sino Biological
Amount	1 mg
Quantity options	1 mg 10 ug 2 mg 4 mg 50 ug 500 ug
Category	Oncology Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Adhesion Molecules By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Obesity Lipoprotein Receptors & Associated Proteins By Organ Bladder Cancer
Type	Proteins
Specific against	Human (Homo sapiens)
Host	Human
Conjugate/Tag	HIS
Purity	> (76.6 + 19.4)% as determined by SDS-PAGE.
Sequence	Met1-Gln692
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	FH3,HCHOLA3,LDLCQ1,NARC-1,NARC1,PC9
Similar products	NARC1
Available
Manufacturer - Type	Protein
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	PCSK9
Protein Construction	A DNA sequence encoding the human PCSK9 (AAV67948.1, with mutation Asp 374 Tyr) (Met 1-Gln 692) was expressed with a polyhistidine tag at the C-terminus.
Expressed Host	Human Cells
Bio-Activity	Measured by its binding ability in a functional ELISA. Immobilized human PCSK9-His(D374Y)at 10 ug/ml (100 ul /well) can bind biotinylated LDLR-His(Cat:10231-H08H) , The EC50 of biotinylated LDLR-His (Cat:10231-H08H) is 20-60ng/ml.
Endotoxin	< 1.0 EU per ug protein as determined by the LAL method.
Predicted N Terminal	Gln 31
Molecule Mass	The recombinant human PCSK9 consists 673 amino acids and predicts a molecular mass of 72.6 kDa.
Formulation	Lyophilized from sterile PBS, pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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