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Human TGFBR2 Protein, hFc Tag

Human TGFBR2 Protein, hFc Tag

Item no.	DIM-PME101017-50ug
Manufacturer	DIMA Biotechnology
Amount	50 ug
Quantity options	100 ug 10 ug 50 ug
Category	Oncology Neuroscience Neuroinflammation By Cell Type Carcinoma Glioma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Mesothelioma By Organ Colorectal Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated, Fc
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AAT3,FAA3,LDS1B,LDS2,LDS2B,MFS2,RIIC,TAAD2,TBR-ii,TBRII,TGFbeta-RII,TGFR-2
Shipping Condition	Room temperature
Available
Manufacturer - Category	ECD Proteins
Manufacturer - Targets	TGFBR2
Manufacturer - Conjugate / Tag	C-Human Fc Tag, Unconjugated
Storage Conditions	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Molecular Weight	The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide. The apparent molecular mass of TGFBR2-hFc is approximately 55-70 kDa due to glycosylation.
Buffer	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Purification	affinity purification
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
Molecular Characterization	TGFBR2(Thr23-Asp159) hFc(Glu99-Ala330)
Description	Recombinant human TGFBR2 protein with C-terminal human Fc tag
Reconstitution	Reconstitute with deionized water
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 9/4/2025

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