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Glucosylceramide synthase-IN-2

Glucosylceramide synthase-IN-2

Manufacturer	MedChem Express
Category	Peptides & Proteins Enzymes
Type	Enzymes
Specific against	other
Amount	50 mg
Item no.	HY-144267-50mg
CASRN	2597958-02-4
eClass 6.1	25140903
eClass 9.0	42010190
Available
Product Description	Glucosylceramide synthase-IN-2 (compound T-690) is a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 15 nM and 190 nM for human GCS and mouse GCS, respectively.Glucosylceramide synthase-IN-2 exhibits noncompetitive type inhibition with C8-ceramide and UDP-glucose.Glucosylceramide synthase-IN-2 can be used for Gaucher's disease research[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
Molecular Weight	447.41
Clinical Information	No Development Reported
Solubility	DMSO : 100 mg/mL (ultrasonic)
Pathway	Neuronal Signaling
Manufacturers Product type	Reference compound

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