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Glucosylceramide synthase-IN-2

Glucosylceramide synthase-IN-2

Manufacturer	MedChem Express
Category	Peptides & Proteins Enzymes
Type	Enzymes
Specific against	other
Amount	5 mg
Item no.	HY-144267-5mg
CASRN	2597958-02-4
eClass 6.1	25140903
eClass 9.0	42010190
Available
Product Description	Glucosylceramide synthase-IN-2 (compound T-690) is a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 15 nM and 190 nM for human GCS and mouse GCS, respectively.Glucosylceramide synthase-IN-2 exhibits noncompetitive type inhibition with C8-ceramide and UDP-glucose.Glucosylceramide synthase-IN-2 can be used for Gaucher's disease research[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	447.41
Clinical_Information	No Development Reported
Manufacturers Research_Area	Metabolic Disease; Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Glucosylceramide Synthase (GCS)
Pathway	Neuronal Signaling
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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