Recombinant Human S100-A12 Protein

< 0.1 EU/μg of the protein by LAL method.

ice pack

11.42 kDa

The protein is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 proteins include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

C-His

CAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6

Measured by its binding ability in a functional ELISA. Immobilized Human S100A12 Protein at 2 μg/mL (100 μL/well) can bind AGER with a linear range of 1. 95-14. 13 ng/mL.

11.42 kDa