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Recombinant Human INHIBIN BETA B

Recombinant Human INHIBIN BETA B

Manufacturer	Raybiotech
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Amount	5 ug
Item no.	229-20216
eClass 6.1	34160400
eClass 9.0	42020190
Available
Short Description	Purified recombinant Inhibin Beta B expressed in High-5 insect cells
Introduction	Inhibin Beta B, otherwise known as Activin B, is a member of the transforming growth factor-beta (TGF-B) family, which signals through the ActRII receptor (Activin Receptor type II), and acts as a regulator of hormone secretion from the pituitary, hypothalamic and gonadal glands. Inhibin Beta B is a homodimer of the inhibin/activin beta-B chain, and is involved in several aspects of embryonic development, as well as haematopoiesis and osteogenesis, and also acts as a modulator of FSH (follicle-stimulating hormone) secretion and haemoglobin synthesis.
Protein Name	INHIBIN BETA B
Molecular Weight (kDa)	25.6kD (115 amino acid Beta B homodimer)
Purity	>95% by SDS PAGE and HPLC analysis
Formulation	10mM Sodium citrate.
Concentration	ca.0.5 mg/ml after reconstitution
Preservative	5% Trehalose
Endotoxin Level	<1EU/ug
Protein Type	Recombinant Protein
Recommended Applications	Functional Assays
Biological activity	The ED₅₀ as determined by its ability to inhibit the proliferation of murine MPC-11 cells is ? 2ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Reconstitution	Reconstitute with 10ul 10mM sodium citrate pH 3, 0. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution.
Storage/stability	Prior to reconstitution store at +4° C. After reconstitution store at -20° C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.