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RANKL / OPGL / TNFSF11 / CD254 Neutralizing Antibody

RANKL / OPGL / TNFSF11 / CD254 Neutralizing Antibody

Item no.	11682-R001-200
Manufacturer	Sino Biological
Amount	200 ug
Quantity options	200 ug 500 ug
Category	Oncology Antibodies Cell Biology Cell Culture Cytokines Primary Antibodies By Organ Lymphatic System Cancer
Type	Antibody Monoclonal
Clone	R001
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	sino
Available
Manufacturer - Type	Antibody
Storage Conditions	This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Antigen molecule name	TNFSF11
Immunogen	Recombinant Human RANKL / OPGL / TNFSF11 / CD254 Protein (Catalog#11682-HNCH)
Purification	Protein A
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human RANKL / OPGL / TNFSF11 / CD254 (rh RANKL / OPGL / TNFSF11 / CD254; Catalog#11682-HNCH; O14788-2; Gly63-Asp244) and was produced using recombinant antibody technology.
Specificity	Human RANKL / OPGL / TNFSF11 / CD254
Buffer	0.2 um filtered solution in Histidine and Arginine buffer containing 120mM NaCl, 0.02% Tween 80, pH6.0
Endotoxin	< 0.23 EU/mg
No cross-reactivity	No cross-reactivity with Mouse TNFSF11 (50343-M01H) in ELISA assay
Cross reactivity	Has cross-reactivity with Cynomolgus TNFSF11 (90301-C01H) in ELISA assay
Block	This TNFSF11 Neutralizing Antibody can block the binding of recombinant TNFSF11 (11682-HNCH) to its recombinant receptor TNFRSF11A (16078-H08H) and TNFRSF11B (10271-H08H).
Neutralization	The neutralization activity of TNFSF11 Neutralizing Antibody is Measured by its ability to neutralize TNFSF11 induced osteoclast-like cell formation in RAW 264.7 mouse macrophages. The Neutralization titer (IC50) is typically 4-16 ng/mL in the presence of 30 ng/mL Recombinant Human RANKL/OPGL/TNFSF11/CD254.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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11682-R001-200-datasheet.pdf

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Amount: 200 ug

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