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Anti-SPTA1 antibody

Anti-SPTA1 antibody

Manufacturer	St John's Laboratory
Category	Neuroscience Neural Lineage Markers Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	STJ114233-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P02549
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
Gene ID	6708
Gene symbol	SPTA1
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 940-1160 of human SPTA1 (NP_003117. 2).
Short Description	Rabbit polyclonal against SPTA1
Cellular localization	Cytoplasm Cytoskeleton Cell Cortex
Molecular weight	Calculated: 279kDa/280kDa. Observed: 300kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Spectrin Alpha Chain-Erythrocytic 1 antibody Anti-Erythroid Alpha-Spectrin antibody Anti-SPTA1 SPTA antibody
Protein name	Spectrin Alpha Chain-Erythrocytic 1 Erythroid Alpha-Spectrin
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	SPTA1_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 5/23/2024