Anti-ATP1B1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P05026

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+-ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.

ATP1B1

Rabbit polyclonal against ATP1B1

Cell Membrane
Single-Pass Type Ii Membrane Protein
Sarcolemma
Colocalizes With Obscn At The Intercalated Disk And Sarcolemma In Cardiomyocytes
Localizes In Long Striations At The Level Of Z And M Lines

WB 1:500-1:2000

Sodium/Potassium-Transporting Atpase Subunit Beta-1
Sodium/Potassium-Dependent Atpase Subunit Beta-1

AT1B1_HUMAN