Anti-NR1I2 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O75469

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

NR1I2

Rabbit polyclonal against NR1I2

Nucleus

WB 1:500-1:2000 IHC 1:50-1:200

Nuclear Receptor Subfamily 1 Group I Member 2
Orphan Nuclear Receptor Par1
Orphan Nuclear Receptor Pxr
Pregnane X Receptor
Steroid And Xenobiotic Receptor
Sxr

NR1I2_HUMAN