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Anti-STAT5B antibody

Anti-STAT5B antibody

Manufacturer	St John's Laboratory
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse
Isotype	IgG
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	STJ114234-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P51692
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Gene ID	6777
Gene symbol	STAT5B
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human STAT5B (NP_036580. 2).
Short Description	Rabbit polyclonal against STAT5B
Cellular localization	Cytoplasm Nucleus Translocated Into The Nucleus In Response To Phosphorylation
Molecular weight	Calculated: 89kDa. Observed: 90kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Signal Transducer And Activator Of Transcription 5b antibody Anti-STAT5B antibody
Protein name	Signal Transducer And Activator Of Transcription 5b
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	STA5B_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 5/23/2024