Manufacturer |
St John's Laboratory
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human |
Isotype |
IgG |
Applications |
WB |
Amount |
50ul |
Host |
Rabbit |
Item no. |
STJ114200-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q10589 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 49-161 of human BST2 (NP_004326. 1). |
Short Description |
Rabbit polyclonal against BST2 |
Tissue specificity |
Predominantly expressed in liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal muscle and brain. Overexpressed in multiple myeloma cells. Highly expressed during B-cell development, from pro-B precursors to plasma cells. Highly expressed on T-cells, monocytes, NK cells and dendritic cells (at protein level). |
Cellular localization |
Golgi ApparatusTrans-Golgi NetworkCell MembraneSingle-Pass Type Ii Membrane ProteinLipid-AnchorGpi-AnchorLate EndosomeMembrane RaftCytoplasmApical Cell MembraneShuttles Between The Cell MembraneWhere It Is Present Predominantly In Membrane/Lipid RaftsAnd The Trans-Golgi NetworkHiv-1 Vpu And Hiv-2 Env Can Target It To The Trans-Golgi Network Thus Sequestering It Away From Virus Assembly Sites On The Cell MembraneTargeted To Late Endosomes Upon Kshv Infection And Subsequent UbiquitinationForms A Complex With Mmp14 And Localizes To The Cytoplasm |
Molecular weight |
Calculated: 18kDa/19kDa. Observed: 35-40kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Bone Marrow Stromal Antigen 2 antibodyAnti-Bst-2 antibodyAnti-Hm1.24 Antigen antibodyAnti-Tetherin antibodyAnti-Cd Antigen Cd317 antibodyAnti-BST2 antibody |
Protein name |
Bone Marrow Stromal Antigen 2Bst-2Hm1.24 AntigenTetherinCd Antigen Cd317 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.