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Anti-CD59 antibody

Anti-CD59 antibody

Manufacturer	St John's Laboratory
Category	Neuroscience Neuroinflammation Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	STJ114286-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P13987
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Gene ID	966
Gene symbol	CD59
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 26-128 of human CD59 (NP_001120695. 1).
Short Description	Rabbit polyclonal against CD59
Cellular localization	Cell Membrane Lipid-Anchor Gpi-Anchor Secreted Soluble Form Found In A Number Of Tissues
Molecular weight	Calculated: 14kDa. Observed: 14kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Cd59 Glycoprotein antibody Anti-1f5 Antigen antibody Anti-20 Kda Homologous Restriction Factor antibody Anti-Hrf-20 antibody Anti-Hrf20 antibody Anti-Mac-Inhibitory Protein antibody Anti-Mac-Ip antibody Anti-Mem43 Antigen antibody Anti-Membrane Attack Complex Inhibition Factor antibody Anti-Macif antibody Anti-Membrane Inhibitor Of Reactive Lysis antibody Anti-Mirl antibody Anti-Protectin antibody Anti-Cd Antigen Cd59 antibody Anti-CD59 MIC11 MIN1 MIN2 MIN3 MSK21 antibody
Protein name	Cd59 Glycoprotein 1f5 Antigen 20 Kda Homologous Restriction Factor Hrf-20 Hrf20 Mac-Inhibitory Protein Mac-Ip Mem43 Antigen Membrane Attack Complex Inhibition Factor Macif Membrane Inhibitor Of Reactive Lysis Mirl Protectin Cd Antigen Cd59
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	CD59_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 5/23/2024