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Anti-CFH antibody

Anti-CFH antibody

Manufacturer	St John's Laboratory
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	STJ115641-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P08603
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID	3075
Gene symbol	CFH
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 270-445 of human CFH (NP_001014975. 1).
Short Description	Rabbit polyclonal against CFH
Tissue specificity	Expressed in the retinal pigment epithelium (at protein level). CFH is one of the most abundant complement components in blood where the liver is the major source of CFH protein in vivo. in addition, CFH is secreted by additional cell types including monocytes, fibroblasts, or endothelial cells.
Cellular localization	Secreted
Molecular weight	Calculated: 51kDa/139kDa. Observed: 139kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Complement Factor H antibody Anti-H Factor 1 antibody Anti-CFH HF HF1 HF2 antibody
Protein name	Complement Factor H H Factor 1
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	CFAH_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 5/23/2024