Comparison

Sulindac European Partner

Item no. TMO-T0459-10mg
Manufacturer TargetMol
CASRN 38194-50-2
Amount 10 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 2 mg 500 mg 50 mg
Category
Type Molecules
Specific against other
Purity 0,98
Smiles C(=C/1\C=2C(C(CC(O)=O)=C1C)=CC(F)=CC2)\C3=CC=C(S(C)=O)C=C3
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias Clinoril,MK-231,Sulindac sulfoxide,Arthrocine
Similar products 38194-50-2
Shipping Condition Cool pack
Available
Manufacturer - Targets
Autophagy|||COX
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
356.41
Description
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cyclic guanosine monophosphate-phosphodiesterase (cGMP-PDE), an enzyme that inhibits the normal apoptosis signal pathway; this inhibition permits the apoptotic signal pathway to proceed unopposed, resulting in apoptotic cell death.
Pathways
Autophagy|||Immunology/Inflammation|||Neuroscience
Formulate
C20H17FO3S

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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