« Back
Home /
Sulindac

Sulindac

Item no.	TMO-T0459-1ml
Manufacturer	TargetMol
CASRN	38194-50-2
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 2 mg 500 mg 50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	C(=C/1\C=2C(C(CC(O)=O)=C1C)=CC(F)=CC2)\C3=CC=C(S(C)=O)C=C3
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Clinoril,MK-231,Sulindac sulfoxide,Arthrocine
Similar products	38194-50-2
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|COX
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	356.41
Description	Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cyclic guanosine monophosphate-phosphodiesterase (cGMP-PDE), an enzyme that inhibits the normal apoptosis signal pathway; this inhibition permits the apoptotic signal pathway to proceed unopposed, resulting in apoptotic cell death.
Pathways	Autophagy\|\|\|Immunology/Inflammation\|\|\|Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T0459-1ml-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 1 mL

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question