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IL4R Antibody (Phospho-Tyr497) (OASG03842)

IL4R Antibody (Phospho-Tyr497) (OASG03842)

Item no.	OASG03842
Manufacturer	AVIVA Systems Biology
Amount	100 uL
Category	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF, IHC
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Molecular weight	90 kDa
Product format	Liquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene id	3566
Reconstitution and storage	Store at -20° C, and avoid repeat freeze-thaw cycles.
Description of target	Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality	Polyclonal
Immunogen	Synthesized peptide derived between 440-520 aa from human IL-4Ralpha around the phosphorylation site of Y497.
Drywet	Wet Ice
Storage	IL4R

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 6/26/2025

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