Recombinant Human herpesvirus 1 Tegument protein VP16 (UL48)

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.

Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection (By similarity).By similarity1 Publication
May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.

Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.

Virion tegument, Host nucleus

Full Length

Tris-based buffer, 50% glycerol