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Recombinant Human Proliferation marker protein Ki-67(MKI67),partial

Recombinant Human Proliferation marker protein Ki-67(MKI67),partial

Manufacturer	Cusabio
Category	Oncology Neuroscience Neural Lineage Markers Neural Development Peptides & Proteins Recombinant Proteins By Organ Lung Cancer Bladder Cancer Breast Cancer Adhesion Molecule Markers
Type	Proteins Recombinant
Specific against	other
Format	Liquid or Lyophilized powder
Amount	50ug
Host	E.coli
Item no.	CSB-EP014597HU(A5)-50
eClass 6.1	34160400
eClass 9.0	42020190
Available
Research Topic	Cancer
Uniprot ID	P46013
Gene Names	MKI67
Organism	Homo sapiens (Human)
AA Sequence	TKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADK EPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRA PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIP CKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVG KLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLD AEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPG HTEELANGAADSFTSAPKQTPDSGKPLKISRRVLR APKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRG GGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVA PRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSND MKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQ ITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDG ARKPIPRDKVTENKRCLRSARQNESSQPKVAEESG GQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQP AASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKK IRTRSHRDSEDI
Expression Region	2720-3256aa
Sequence Info	Partial
Source	E.coli
Tag Info	N-terminal 6xHis-SUMO-tagged
MW	75.1 kDa
Relevance	Thought to be required for maintaining cell proliferation.
Reference	"The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins."Schlueter C., Duchrow M., Wohlenberg C., Becker M.H.G., Key G., Flad H.-D., Gerdes J.J. Cell Biol. 123:513-522(1993)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly
Subcellular Location	Chromosome, Nucleus, Nucleus, nucleolus
Tag Information	N-terminal 6xHis-SUMO-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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